| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50290902 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_29485 (CHEMBL641719) |
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| Ki | 8±n/a nM |
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| Citation |  Ha, SB; Melman, N; Jacobson, KA; Nair, V New base-altered adenosine analogues: Synthesis and affinity at adenosine A1 and A2A receptors Bioorg Med Chem Lett7:3085-3090 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50290902 |
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| n/a |
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| Name | BDBM50290902 |
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| Synonyms: | (2R,3S,4R,5R)-2-Hydroxymethyl-5-[6-(pyrrolidin-1-ylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | CHEMBL104580 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H20N6O4 |
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| Mol. Mass. | 336.3464 |
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| SMILES | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NN3CCCC3)ncnc12 |
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| Structure | 
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