| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM50291595 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_139961 |
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| Ki | 1620±n/a nM |
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| Citation |  Hudkins, RL; DeHaven-Hudkins, DL; Doukas, P Design of dual acting anticonvulsant-antimuscarinic succinimide and hydantoin derivatives Bioorg Med Chem Lett7:979-984 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51390.46 |
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| Organism: | RAT |
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| Description: | P08482 |
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| Residue: | 460 |
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| Sequence: | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM50291595 |
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| n/a |
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| Name | BDBM50291595 |
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| Synonyms: | 1'-(4-diisopropylamino-2-butynyl)spiro[9H-fluorene-9,3'-(tetrahydro-1'H-pyrrole)]-2',5'-dione | CHEMBL178323 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H28N2O2 |
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| Mol. Mass. | 400.5127 |
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| SMILES | CC(C)N(CC#CCN1C(=O)CC2(C1=O)c1ccccc1-c1ccccc21)C(C)C |
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| Structure | 
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