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TargetGTPase HRas
LigandBDBM50072338
Substrate/Competitorn/a
Meas. Tech.ChEBML_82665
IC50>300000±n/a nM
Citation Baraldi PGCacciari BGuiotto ALeoni ARomagnoli RSpalluto GMongelli NHoward PWThurston DEBianchi NGambari R Design, synthesis and biological activity of a pyrrolo [2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid. Bioorg Med Chem Lett 8:3019-24 (1999) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
GTPase HRas
Name:GTPase HRas
Synonyms:GTPase HRas, N-terminally processed | H-Ras | H-Ras-1 | HRAS1 | Ha-Ras | His6-Ha-Ras-CVLS | Transforming protein p21 | Transforming protein p21/H-Ras-1 | Wild-type Ha-Ras | c-H-ras | p21ras
Type:Other Protein Type
Mol. Mass.:21293.37
Organism:Homo sapiens (Human)
Description:P01112
Residue:189
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPG
CMSCKCVLS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50072338
n/a
NameBDBM50072338
Synonyms:3-((S)-7-Methoxy-5-oxo-2,3,5,11a-tetrahydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-8-yloxy)-propionic acid methyl ester | CHEMBL300580
TypeSmall organic molecule
Emp. Form.C17H20N2O5
Mol. Mass.332.3511
SMILESCOC(=O)CCOc1cc2N=C[C@@H]3CCCN3C(=O)c2cc1OC |c:10|
Structure
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