| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
|---|
| Ligand | BDBM50081831 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_33606 |
|---|
| Ki | 3±n/a nM |
|---|
| Citation |  Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C Design and synthesis of novel dihydropyridine alpha-1a antagonists. Bioorg Med Chem Lett9:2843-8 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-1A adrenergic receptor |
|---|
| Name: | Alpha-1A adrenergic receptor |
|---|
| Synonyms: | ADA1A_HUMAN | ADRA1A | ADRA1C | Adrenergic alpha1A | Alpha 1A-adrenoceptor | Alpha 1A-adrenoreceptor | Alpha adrenergic receptor 1a | Alpha-1C adrenergic receptor | Alpha-adrenergic receptor 1c | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha1 | adrenergic Alpha1C |
|---|
| Type: | Cell-surface receptors |
|---|
| Mol. Mass.: | 51511.67 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35348 |
|---|
| Residue: | 466 |
|---|
| Sequence: | MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
APAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTL
HPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSARITVSKDQSSCT
TARVRSKSFLQVCCCVGPSTPSLDKNHQVPTIKVHTISLSENGEEV
|
|
|
|---|
| BDBM50081831 |
|---|
| n/a |
|---|
| Name | BDBM50081831 |
|---|
| Synonyms: | 2-(2-Amino-ethoxymethyl)-6-ethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide} 3-ethylamide | CHEMBL95253 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C40H50N6O5 |
|---|
| Mol. Mass. | 694.8622 |
|---|
| SMILES | CCNC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(CC)N=C1COCCN)c1ccc(cc1)[N+]([O-])=O |c:38,t:34| |
|---|
| Structure | 
|
|---|
Search and Browse
