| Reaction Details |
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 | Report a problem with these data |
| Target | Vanilloid receptor |
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| Ligand | BDBM50082245 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_215486 |
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| Ki | 45200±n/a nM |
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| Citation |  Lee J; Park SU; Kim JY; Kim JK; Lee J; Oh U; Marquez VE; Beheshti M; Wang QJ; Modarres S; Blumberg PM 3-Acyloxy-2-phenalkylpropyl amides and esters of homovanillic acid as novel vanilloid receptor agonists. Bioorg Med Chem Lett 9:2909-14 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Vanilloid receptor |
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| Name: | Vanilloid receptor |
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| Synonyms: | Capsaicin receptor | OTRPC1 | Transient receptor potential cation channel subfamily V member 1 (TRPV1) | Vanilloid Receptor 1 (TRPV1, VR1) | Vanilloid VR1 | Vanilloid receptor 1 (VRI/TRPV1) | Vanilloid receptor type 1-like | Vanilloid receptor type 1-like (TrpV1/Vr1) | osm-9-like TRP channel 1 |
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| Type: | Transient Receptor |
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| Mol. Mass.: | 94956.12 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | O35433 |
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| Residue: | 838 |
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| Sequence: | MEQRASLDSEESESPPQENSCLDPPDRDPNCKPPPVKPHIFTTRSRTRLFGKGDSEEASP
LDCPYEEGGLASCPIITVSSVLTIQRPGDGPASVRPSSQDSVSAGEKPPRLYDRRSIFDA
VAQSNCQELESLLPFLQRSKKRLTDSEFKDPETGKTCLLKAMLNLHNGQNDTIALLLDVA
RKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTK
GRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVD
NTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYILQREIHEP
ECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLNR
LLQDKWDRFVKRIFYFNFFVYCLYMIIFTAAAYYRPVEGLPPYKLKNTVGDYFRVTGEIL
SVSGGVYFFFRGIQYFLQRRPSLKSLFVDSYSEILFFVQSLFMLVSVVLYFSQRKEYVAS
MVFSLAMGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFSTAVVTLIE
DGKNNSLPMESTPHKCRGSACKPGNSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFI
ILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKAF
RSGKLLQVGFTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRSG
RVSGRNWKNFALVPLLRDASTRDRHATQQEEVQLKHYTGSLKPEDAEVFKDSMVPGEK
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| BDBM50082245 |
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| n/a |
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| Name | BDBM50082245 |
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| Synonyms: | Acetic acid 2-{[2-(4-hydroxy-3-methoxy-phenyl)-acetylamino]-methyl}-4-phenyl-butyl ester | CHEMBL99326 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27NO5 |
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| Mol. Mass. | 385.4535 |
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| SMILES | COc1cc(CC(=O)NCC(CCc2ccccc2)COC(C)=O)ccc1O |
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| Structure | 
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