| Reaction Details |
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 | Report a problem with these data |
| Target | Plasminogen |
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| Ligand | BDBM50074918 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_155604 |
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| Ki | 120±n/a nM |
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| Citation |  Garrett, GS; McPhail, SJ; Tornheim, K; Correa, PE; McIver, JM Synthesis of potent and selective inhibitors of human plasma kallikrein. Bioorg Med Chem Lett9:301-6 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Plasminogen |
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| Name: | Plasminogen |
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| Synonyms: | PLMN_RAT | Plasmin | Plasminogen | Plg |
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| Type: | Protein |
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| Mol. Mass.: | 90541.87 |
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| Organism: | Rattus norvegicus |
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| Description: | Q01177 |
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| Residue: | 812 |
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| Sequence: | MDHKEIILLFLLFLKPGQGDSLDGYVSTQGASLHSLTKKQLAAGSIADCLAKCEGETDFI
CRSFQYHSKEQQCVIMAENSKTSSIIRMRDVILFEKRVYLSECKTGIGKGYRGTMSKTKT
GVTCQKWSDTSPHVPKYSPSTHPSEGLEENYCRNPDNDEQGPWCYTTDPDQRYEYCNIPE
CEEECMYCSGEKYEGKISKTMSGLDCQSWDSQSPHAHGYIPAKFPSKNLKMNYCRNPDGE
PRPWCFTTDPNKRWEYCDIPRCTTPPPPPGPTYQCLKGRGENYRGTVSVTASGKTCQRWS
EQTPHRHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSQLRWEYCEIPSCGSSVSPDQ
SDSSVLPEQTPVVQECYQGNGKSYRGTSSTTNTGKKCQSWVSMTPHSHSKTPANFPDAGL
EMNYCRNPDNDQRGPWCFTTDPSVRWEYCNLKRCSETGGGVAESAIVPQVPSAPGTSETD
CMYGNGKEYRGKTAVTAAGTPCQEWAAQEPHSHRIFTPQTNPRAGLEKNYCRNPDGDVNG
PWCYTMNPRKLYDYCNIPLCASLSSFECGKPQVEPKKCPGRVVGGCVANPHSWPWQISLR
TRFSGQHFCGGTLISPEWVLTAAHCLEKSSRPEFYKVILGAHEERILGSDVQQIAVTKLV
LEPNDADIALLKLSRPATITDNVIPACLPSPNYVVADRTLCYITGWGETKGTPGAGRLKE
AQLPVIENKVCNRAEYLNNRVKSTELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVT
SWGLGCARPNKPGVYVRVSRYVNWIEREMRND
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| BDBM50074918 |
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| n/a |
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| Name | BDBM50074918 |
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| Synonyms: | ((R)-2,2-Dimethyl-1-{(S)-2-phenyl-1-[3,3,3-trifluoro-1-(4-guanidino-benzyl)-2-oxo-propylcarbamoyl]-ethylcarbamoyl}-propyl)-carbamic acid adamantan-1-yl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C37H48F3N6O5 |
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| Mol. Mass. | 713.8089 |
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| SMILES | CC(C)(C)[C@@H](NC(=O)OC12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC(Cc1ccc(NC(N)=[NH2+])cc1)C(=O)C(F)(F)F |TLB:12:13:17:11.10.16,THB:14:15:10:13.18.12,14:13:10:15.17.16,12:11:17:13.18.14| |
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| Structure | 
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