| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 4 |
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| Ligand | BDBM50088762 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_45432 |
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| Ki | 4±n/a nM |
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| Citation |  Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: synthesis of N-morpholylthiocarbonylsulfenylamino aromatic/heterocyclic sulfonamides and their interaction with isozymes I, II and IV. Bioorg Med Chem Lett10:1117-20 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 4 |
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| Name: | Carbonic anhydrase 4 |
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| Synonyms: | CA-IV | CA4 | CAH4_BOVIN | Carbonate dehydratase IV | Carbonic Anhydrase IV | Carbonic anhydrase | Carbonic anhydrase 4 |
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| Type: | Enzyme |
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| Mol. Mass.: | 35152.74 |
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| Organism: | Bos taurus (bovine) |
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| Description: | Bovine isozyme, isolated from lung microsomes |
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| Residue: | 312 |
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| Sequence: | MRLLLALLVLAAAPPQARAASHWCYQIQVKPSNYTCLEPDEWEGSCQNNRQSPVNIVTAK
TQLDPNLGRFSFSGYNMKHQWVVQNNGHTVMVLLENKPSIAGGGLSTRYQATQLHLHWSR
AMDRGSEHSFDGERFAMEMHIVHEKEKGLSGNASQNQFAEDEIAVLAFMVEDGSKNVNFQ
PLVEALSDIPRPNMNTTMKEGVSLFDLLPEEESLRHYFRYLGSLTTPTCDEKVVWTVFQK
PIQLHRDQILAFSQKLFYDDQQKVNMTDNVRPVQSLGQRQVFRSGAPGLLLAQPLPTLLA
PVLACLTVGFLR
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| BDBM50088762 |
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| n/a |
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| Name | BDBM50088762 |
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| Synonyms: | CHEMBL13614 | N,N-dialkylthio-carbonylsulfenylamino derivative |
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| Type | Small organic molecule |
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| Emp. Form. | C13H16N6O5S5 |
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| Mol. Mass. | 496.628 |
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| SMILES | NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccc(NSC(=S)N3CCOCC3)cc2)s1 |
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| Structure | 
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