| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM21220 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_29424 |
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| Ki | 1±n/a nM |
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| Citation |  Keeling, SE; Albinson, FD; Ayres, BE; Butchers, PR; Chambers, CL; Cherry, PC; Ellis, F; Ewan, GB; Gregson, M; Knight, J; Mills, K; Ravenscroft, P; Reynolds, LH; Sanjar, S; Sheehan, MJ The discovery and synthesis of highly potent, A2a receptor agonists. Bioorg Med Chem Lett10:403-6 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor | AA1R_CAVPO | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor | Adenosine Receptor A1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36501.39 |
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| Organism: | GUINEA PIG |
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| Description: | ADENOSINE A1 ADORA1 GUINEA PIG::P47745 |
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| Residue: | 326 |
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| Sequence: | MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPEPPIDEDLPEEKVDD
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| BDBM21220 |
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| n/a |
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| Name | BDBM21220 |
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| Synonyms: | (2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide | Adenosine analog, 3 | Adenosine, N6-Ethyl-carboxamido | Adenosine-5-(N-ethylcarboxamide) | CHEMBL464859 | N-Ethylcarboxamidoadenosine | NECA |
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| Type | Antineoplastic Agent |
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| Emp. Form. | C12H16N6O4 |
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| Mol. Mass. | 308.2932 |
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| SMILES | CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |
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| Structure | 
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