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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Alpha-2A adrenergic receptor | ||
| Ligand | BDBM50087148 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_33064 | ||
| Ki | 1.3±n/a nM | ||
| Citation |  Zheng, W; Lei, L; Lalchandani, S; Sun, G; Feller, DR; Miller, DD Yohimbine dimers exhibiting binding selectivities for human alpha2a- versus alpha2b-adrenergic receptors. Bioorg Med Chem Lett10:627-30 (2000) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Alpha-2A adrenergic receptor | |||
| Name: | Alpha-2A adrenergic receptor | ||
| Synonyms: | ADA2A_HUMAN | ADRA2A | ADRA2R | ADRAR | Adrenergic alpha2A | Adrenergic receptor alpha | Alpha-2 adrenergic receptor subtype C10 | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | alpha-2A adrenergic receptor [Homo sapiens] | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 48979.91 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P08913 | ||
| Residue: | 450 | ||
| Sequence: |
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| BDBM50087148 | |||
| n/a | |||
| Name | BDBM50087148 | ||
| Synonyms: | 1N-{9-[2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2-a]b-carbolin-1-ylcarboxamido]nonyl}-2-hydroxy-(1R,2S,4aR,13bS,14aS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2 ;dihydrochloride | CHEMBL539606 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C49H66N6O4 | ||
| Mol. Mass. | 803.0861 | ||
| SMILES | O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2[C@H]1C(=O)NCCCCCCCCCNC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 | ||
| Structure | 
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