Reaction Details | |||
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Target | Nociceptin receptor | ||
Ligand | BDBM50087693 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_146124 | ||
Ki | 2±n/a nM | ||
Citation | Röver, S; Wichmann, J; Jenck, F; Adam, G; Cesura, AM ORL1 receptor ligands: structure-activity relationships of 8-cycloalkyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-ones. Bioorg Med Chem Lett10:831-4 (2000) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
Nociceptin receptor | |||
Name: | Nociceptin receptor | ||
Synonyms: | Nociceptin/Orphanin FQ, NOP receptor | Nociceptin/mu opioid receptor | OPRX_RAT | Oor | Oprl | Oprl1 | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 40531.08 | ||
Organism: | RAT | ||
Description: | Nociceptin/Orphanin FQ, NOP receptor 0 RAT::P35370 | ||
Residue: | 367 | ||
Sequence: |
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BDBM50087693 | |||
n/a | |||
Name | BDBM50087693 | ||
Synonyms: | 1-Phenyl-8-(4-propyl-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one | CHEMBL166445 | ||
Type | Small organic molecule | ||
Emp. Form. | C22H33N3O | ||
Mol. Mass. | 355.5169 | ||
SMILES | CCC[C@H]1CC[C@H](CC1)N1CCC2(CC1)N(CNC2=O)c1ccccc1 |wU:6.9,3.2,(1.92,-2.67,;3.46,-2.68,;4.23,-4.01,;5.77,-4.02,;6.54,-2.69,;8.08,-2.69,;8.83,-4.02,;8.08,-5.35,;6.54,-5.35,;10.37,-4.02,;11.14,-2.68,;12.68,-2.67,;13.45,-4.01,;12.68,-5.34,;11.14,-5.34,;14.33,-5.26,;15.8,-4.79,;15.8,-3.25,;14.36,-2.76,;13.87,-1.31,;13.87,-6.7,;12.35,-7.03,;11.88,-8.49,;12.91,-9.64,;14.43,-9.32,;14.89,-7.85,)| | ||
Structure |