| Reaction Details |
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 | Report a problem with these data |
| Target | Fructose-1,6-bisphosphatase 1 |
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| Ligand | BDBM4626 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_157940 |
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| IC50 | 340±n/a nM |
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| Citation |  Wright, SW; Hageman, DL; McClure, LD; Carlo, AA; Treadway, JL; Mathiowetz, AM; Withka, JM; Bauer, PH Allosteric inhibition of fructose-1,6-bisphosphatase by anilinoquinazolines. Bioorg Med Chem Lett11:17-21 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Fructose-1,6-bisphosphatase 1 |
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| Name: | Fructose-1,6-bisphosphatase 1 |
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| Synonyms: | F16P1_PIG | FBP | FBP1 | Fructose-1,6-bisphosphatase | Fructose-1,6-bisphosphatase 1 (FBPase) |
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| Type: | Protein |
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| Mol. Mass.: | 36781.07 |
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| Organism: | Sus scrofa (Pig) |
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| Description: | Liver FBPase (P00636) |
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| Residue: | 338 |
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| Sequence: | MTDQAAFDTNIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGI
AGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDP
LDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVN
GVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAP
YGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGK
EAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHAAK
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| BDBM4626 |
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| n/a |
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| Name | BDBM4626 |
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| Synonyms: | Anilinoquinazoline deriv. 9 | CHEMBL301018 | N-(3-chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C16H13ClFN3O2 |
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| Mol. Mass. | 333.745 |
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| SMILES | COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OC |
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| Structure | 
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