| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM50128411 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_145276 |
|---|
| Ki | 1.9±n/a nM |
|---|
| Citation |  Wentland, MP; Lou, R; Dehnhardt, CM; Duan, W; Cohen, DJ; Bidlack, JM 3-Carboxamido analogues of morphine and naltrexone. synthesis and opioid receptor binding properties. Bioorg Med Chem Lett11:1717-21 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 11165.58 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | P97266 |
|---|
| Residue: | 98 |
|---|
| Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
|
|
|
|---|
| BDBM50128411 |
|---|
| n/a |
|---|
| Name | BDBM50128411 |
|---|
| Synonyms: | 3-desoxy-3-carboxamidonaltrexone | 4-cyclopropylmethyl-17-hydroxy-14-oxo-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-triene-10-carboxamide | CHEMBL56695 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H24N2O4 |
|---|
| Mol. Mass. | 368.4263 |
|---|
| SMILES | NC(=O)c1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
