| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
|---|
| Ligand | BDBM50101343 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_45058 |
|---|
| Ki | 85±n/a nM |
|---|
| Citation |  Mincione, F; Starnotti, M; Menabuoni, L; Scozzafava, A; Casini, A; Supuran, CT Carbonic anhydrase inhibitors: 4-sulfamoyl-benzenecarboxamides and 4-chloro-3-sulfamoyl-benzenecarboxamides with strong topical antiglaucoma properties. Bioorg Med Chem Lett11:1787-91 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 2 |
|---|
| Name: | Carbonic anhydrase 2 |
|---|
| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29250.71 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00918 |
|---|
| Residue: | 260 |
|---|
| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
|
|
|
|---|
| BDBM50101343 |
|---|
| n/a |
|---|
| Name | BDBM50101343 |
|---|
| Synonyms: | (4-Sulfamoyl-benzoylamino)-acetic acid | CHEMBL51385 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H10N2O5S |
|---|
| Mol. Mass. | 258.251 |
|---|
| SMILES | NS(=O)(=O)c1ccc(cc1)C(=O)NCC(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
