| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 4 |
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| Ligand | BDBM50097275 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_219473 |
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| Ki | 6±n/a nM |
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| Citation |  Scozzafava, A; Menabuoni, L; Mincione, F; Mincione, G; Supuran, CT Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties. Bioorg Med Chem Lett11:575-82 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 4 |
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| Name: | Carbonic anhydrase 4 |
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| Synonyms: | CA-IV | CA4 | CAH4_HUMAN | Carbonate dehydratase IV | Carbonic anhydrase | Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV) |
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| Type: | Enzyme |
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| Mol. Mass.: | 35037.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22748 |
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| Residue: | 312 |
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| Sequence: | MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTK
AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD
LPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGF
QPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFRE
PIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLG
PMLACLLAGFLR
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| BDBM50097275 |
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| n/a |
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| Name | BDBM50097275 |
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| Synonyms: | CHEMBL286586 | {{2-[Carboxymethyl-(2-{carboxymethyl-[(2-sulfamoyl-benzothiazol-6-ylcarbamoyl)-methyl]-amino}-ethyl)-amino]-ethyl}-[(2-sulfamoyl-benzothiazol-6-ylcarbamoyl)-methyl]-amino}-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C28H33N9O12S4 |
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| Mol. Mass. | 815.875 |
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| SMILES | NS(=O)(=O)c1nc2ccc(NC(=O)CN(CCN(CCN(CC(O)=O)CC(=O)Nc3ccc4nc(sc4c3)S(N)(=O)=O)CC(O)=O)CC(O)=O)cc2s1 |
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| Structure | 
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