Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50114965 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_79805 |
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IC50 | 8950±n/a nM |
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Citation | Murphy, PV; O'Brien, JL; Gorey-Feret, LJ; Smith, AB Structure-based design and synthesis of HIV-1 protease inhibitors employing beta-D-mannopyranoside scaffolds. Bioorg Med Chem Lett12:1763-6 (2002) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50114965 |
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n/a |
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Name | BDBM50114965 |
Synonyms: | CHEMBL52487 | N-((3S,5R,6S)-3,4,5-Trihydroxy-6-phenoxy-tetrahydro-pyran-2-ylmethyl)-acetamide |
Type | Small organic molecule |
Emp. Form. | C14H19NO6 |
Mol. Mass. | 297.3038 |
SMILES | CC(=O)NCC1O[C@@H](Oc2ccccc2)[C@@H](O)C(O)[C@@H]1O |
Structure |
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