| Reaction Details |
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 | Report a problem with these data |
| Target | Isoform 4 of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (4) |
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| Ligand | BDBM50366794 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_99589 |
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| IC50 | 42100±n/a nM |
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| Citation |  Novak, KA; Fujii, N; Guy, RK Investigation of the PDZ domain ligand binding site using chemically modified peptides. Bioorg Med Chem Lett12:2471-4 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Isoform 4 of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (4) |
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| Name: | Isoform 4 of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (4) |
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| Synonyms: | KIAA1634 | MAGI3 | MAGI3_HUMAN | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (4) | Membrane-associated guanylate kinase-related 3 | Membrane-associated guanylate kinase-related 3 isoform 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 165630.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_99591 |
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| Residue: | 1506 |
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| Sequence: | MSKTLKKKKHWLSKVQECAVSWAGPPGDFGAEIRGGAERGEFPYLGRLREEPGGGTCCVV
SGKAPSPGDVLLEVNGTPVSGLTNRDTLAVIRHFREPIRLKTVKPGKVINKDLRHYLSLQ
FQKGSIDHKLQQVIRDNLYLRTIPCTTRAPRDGEVPGVDYNFISVEQFKALEESGALLES
GTYDGNFYGTPKPPAEPSPFQPDPVDQVLFDNEFDAESQRKRTTSVSKMERMDSSLPEEE
EDEDKEAINGSGNAENRERHSESSDWMKTVPSYNQTNSSMDFRNYMMRDETLEPLPKNWE
MAYTDTGMIYFIDHNTKTTTWLDPRLCKKAKAPEDCEDGELPYGWEKIEDPQYGTYYVDF
TLVAQAGVQWHDLGSLQPPPPGFNHLNQKTQFENPVEEAKRKKQLGQVEIGSSKPDMEKS
HFTRDPSQLKGVLVRASLKKSTMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGD
VIVDINGNCVLGHTHADVVQMFQLVPVNQYVNLTLCRGYPLPDDSEDPVVDIVAATPVIN
GQSLTKGETCMNPQDFKPGAMVLEQNGKSGHTLTGDGLNGPSDASEQRVSMASSGSSQPE
LVTIPLIKGPKGFGFAIADSPTGQKVKMILDSQWCQGLQKGDIIKEIYHQNVQNLTHLQV
VEVLKQFPVGADVPLLILRGGPPSPTKTAKMKTDKKENAGSLEAINEPIPQPMPFPPSII
RSGSPKLDPSEVYLKSKTLYEDKPPNTKDLDVFLRKQESGFGFRVLGGDGPDQSIYIGAI
IPLGAAEKDGRLRAADELMCIDGIPVKGKSHKQVLDLMTTAARNGHVLLTVRRKIFYGEK
QPEDDSSQAFISTQNGSPRLNRAEVPARPAPQEPYDVVLQRKENEGFGFVILTSKNKPPP
GVIPHKIGRVIEGSPADRCGKLKVGDHISAVNGQSIVELSHDNIVQLIKDAGVTVTLTVI
AEEEHHGPPSGTNSARQSPALQHRPMGQSQANHIPGDRSALEGEIGKDVSTSYRHSWSDH
KHLAQPDTAVISVVGSRHNQNLGCYPVELERGPRGFGFSLRGGKEYNMGLFILRLAEDGP
AIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLRPGTGLIPDHGDWDIN
NPSSSNVIYDEQSPLPPSSHFASIFEESHVPVIEESLRVQICEKAEELKDIVPEKKSTLN
ENQPEIKHQSLLQKNVSKRDPPSSHGHSNKKNLLKVENGVTRRGRSVSPKKPASQHSEEH
LDKIPSPLKNNPKRRPRDQSLSPSKGENKSCQVSTRAGSGQDQCRKSRGRSASPKKQQKI
EGSKAPSNAEAKLLEGKSRRIAGYTGSNAEQIPDGKEKSDVIRKDAKQNQLEKSRTRSPE
KKIKRMVEKSLPSKMTNKTTSKEVSENEKGKKVTTGETSSSNDKIGENVQLSEKRLKQEP
EEKVVSNKTEDHKGKELEAADKNKETGRFKPESSSPVKKTLITPGPWKVPSGNKVTGTIG
MAEKRQ
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| BDBM50366794 |
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| n/a |
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| Name | BDBM50366794 |
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| Synonyms: | CHEMBL1790637 |
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| Type | Small organic molecule |
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| Emp. Form. | C37H57N9O11 |
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| Mol. Mass. | 803.9022 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(C)=O)[C@H](C)O)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C(C)C)C(=O)NO |
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| Structure | 
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