| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Delta-type opioid receptor |
|---|
| Ligand | BDBM50120146 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_145476 |
|---|
| Ki | 10090±n/a nM |
|---|
| Citation |  Wu, WL; Caplen, MA; Domalski, MS; Zhang, H; Fawzi, A; Burnett, DA Synthesis and structure-activity relationships of aminoalkylazetidines as ORL1 receptor ligands. Bioorg Med Chem Lett12:3157-60 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Delta-type opioid receptor |
|---|
| Name: | Delta-type opioid receptor |
|---|
| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 40382.98 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
|---|
| Residue: | 372 |
|---|
| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
|
|
|
|---|
| BDBM50120146 |
|---|
| n/a |
|---|
| Name | BDBM50120146 |
|---|
| Synonyms: | C-{(S)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-butyl)-azetidin-2-yl]}-methylamine | CHEMBL110933 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H25ClN2 |
|---|
| Mol. Mass. | 328.879 |
|---|
| SMILES | CCCC(N1CC[C@H]1[C@@H](N)c1cccc(Cl)c1)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
