| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Thermolysin |
|---|
| Ligand | BDBM50121454 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_210401 |
|---|
| Ki | 41±n/a nM |
|---|
| Citation |  Kim, J; Glekas, A; McN Sieburth, S Silanediol-based inhibitor of thermolysin. Bioorg Med Chem Lett12:3625-7 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Thermolysin |
|---|
| Name: | Thermolysin |
|---|
| Synonyms: | THER_BACTH | npr |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60097.54 |
|---|
| Organism: | Bacillus thermoproteolyticus |
|---|
| Description: | ChEMBL_1468794 |
|---|
| Residue: | 548 |
|---|
| Sequence: | MKMKMKLASFGLAAGLAAQVFLPYNALASTEHVTWNQQFQTPQFISGDLLKVNGTSPEEL
VYQYVEKNENKFKFHENAKDTLQLKEKKNDNLGFTFMRFQQTYKGIPVFGAVVTSHVKDG
TLTALSGTLIPNLDTKGSLKSGKKLSEKQARDIAEKDLVANVTKEVPEYEQGKDTEFVVY
VNGDEASLAYVVNLNFLTPEPGNWLYIIDAVDGKILNKFNQLDAAKPGDVKSITGTSTVG
VGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDA
PAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQ
TFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEI
GEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGG
THYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQ
AFDAVGVK
|
|
|
|---|
| BDBM50121454 |
|---|
| n/a |
|---|
| Name | BDBM50121454 |
|---|
| Synonyms: | (S)-2-[(Aminomethyl-diphenyl-silanyl)-methyl]-4-methyl-pentan-1-ol | CHEMBL333124 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H29NOSi |
|---|
| Mol. Mass. | 327.5359 |
|---|
| SMILES | CC(C)C[C@@H](CO)C[Si](CN)(c1ccccc1)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
