| Reaction Details |
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 | Report a problem with these data |
| Target | Serum paraoxonase/arylesterase 1 |
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| Ligand | BDBM50127647 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_152860 |
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| IC50 | 3270000±n/a nM |
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| Citation |  Bargota, RS; Akhtar, M; Biggadike, K; Gani, D; Allemann, RK Structure-activity relationship on human serum paraoxonase (PON1) using substrate analogues and inhibitors. Bioorg Med Chem Lett13:1623-6 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serum paraoxonase/arylesterase 1 |
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| Name: | Serum paraoxonase/arylesterase 1 |
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| Synonyms: | A-esterase 1 | Aromatic esterase 1 | K-45 | PON | PON 1 | PON1 | PON1_HUMAN | Paraoxonase (PON1) | Paraoxonase (hPON1) | Paraoxonase 1 (PON1) | Serum aryldialkylphosphatase 1 | Serum paraoxonase 1 (PON1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 39719.73 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P27169 |
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| Residue: | 355 |
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| Sequence: | MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN
GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF
TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG
TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL
LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP
ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
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| BDBM50127647 |
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| n/a |
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| Name | BDBM50127647 |
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| Synonyms: | CHEMBL296745 | Phosphoric acid diethyl ester phenyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C10H15O4P |
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| Mol. Mass. | 230.1975 |
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| SMILES | CCOP(=O)(OCC)Oc1ccccc1 |
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| Structure | 
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