| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidylate kinase |
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| Ligand | BDBM50132286 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_208218 |
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| Ki | 110000±n/a nM |
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| Citation |  Vanheusden, V; Van Rompaey, P; Munier-Lehmann, H; Pochet, S; Herdewijn, P; Van Calenbergh, S Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase. Bioorg Med Chem Lett13:3045-8 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Thymidylate kinase |
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| Name: | Thymidylate kinase |
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| Synonyms: | KTHY_MYCTU | TMPK | Thymidine monophosphate kinase | dTMP kinase | tmk |
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| Type: | PROTEIN |
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| Mol. Mass.: | 22636.29 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | ChEMBL_208218 |
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| Residue: | 214 |
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| Sequence: | MLIAIEGVDGAGKRTLVEKLSGAFRAAGRSVATLAFPRYGQSVAADIAAEALHGEHGDLA
SSVYAMATLFALDRAGAVHTIQGLCRGYDVVILDRYVASNAAYSAARLHENAAGKAAAWV
QRIEFARLGLPKPDWQVLLAVSAELAGERSRGRAQRDPGRARDNYERDAELQQRTGAVYA
ELAAQGWGGRWLVVGADVDPGRLAATLAPPDVPS
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| BDBM50132286 |
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| n/a |
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| Name | BDBM50132286 |
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| Synonyms: | (R)-5-Hydroxymethyl-1-((4S,5R)-4-hydroxy-5-methylphosphate-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione |
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| Type | Small organic molecule |
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| Emp. Form. | C10H13N2O9P |
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| Mol. Mass. | 336.1931 |
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| SMILES | OCc1cn([C@H]2C[C@H](O)[C@@H](COP([O-])([O-])=O)O2)c(=O)[nH]c1=O |
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| Structure | 
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