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TargetImmunoglobulin epsilon Fc receptor
LigandBDBM50132444
Substrate/Competitorn/a
Meas. Tech.ChEBML_163803
EC50 6960±n/a nM
Citation Lai JYCox PJPatel RSadiq SAldous DJThurairatnam SSmith KWheeler DJagpal SParveen SFenton GHarrison TKMcCarthy CBamborough P Potent small molecule inhibitors of spleen tyrosine kinase (Syk). Bioorg Med Chem Lett 13:3111-4 (2003) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Immunoglobulin epsilon Fc receptor
Name:Immunoglobulin epsilon Fc receptor
Synonyms:BLAST-2 | CD_antigen=CD23 | Fc-epsilon-RII | Immunoglobulin E-binding factor | Low affinity immunoglobulin epsilon Fc receptor | Low affinity immunoglobulin epsilon Fc receptor membrane-bound form | Low affinity immunoglobulin epsilon Fc receptor soluble form | Lymphocyte IgE receptor
Type:PROTEIN
Mol. Mass.:36461.84
Organism:Homo sapiens (Human)
Description:ChEMBL_88888
Residue:321
Sequence:
MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA
ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL
SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG
TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHV
DYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESM
GPDSRPDPDGRLPTPSAPLHS
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  Blast E-value cutoff:
BDBM50132444
n/a
NameBDBM50132444
Synonyms:5-{5-Methoxy-3-[2-oxo-5-sulfamoyl-1,2-dihydro-indol-(3Z)-ylidenemethyl]-indol-1-yl}-pentanoic acid ethyl ester | CHEMBL104651 | ethyl 5-(5-methoxy-3-((2-oxo-5-sulfamoylindolin-3-ylidene)methyl)-1H-indol-1-yl)pentanoate
TypeSmall organic molecule
Emp. Form.C25H27N3O6S
Mol. Mass.497.563
SMILESCCOC(=O)CCCCn1cc(\C=C2/C(=O)Nc3ccc(cc23)S(N)(=O)=O)c2cc(OC)ccc12
Structure
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