| Reaction Details |
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 | Report a problem with these data |
| Target | Low affinity immunoglobulin epsilon Fc receptor |
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| Ligand | BDBM50132444 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_163803 |
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| EC50 | 6960±n/a nM |
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| Citation |  Lai, JY; Cox, PJ; Patel, R; Sadiq, S; Aldous, DJ; Thurairatnam, S; Smith, K; Wheeler, D; Jagpal, S; Parveen, S; Fenton, G; Harrison, TK; McCarthy, C; Bamborough, P Potent small molecule inhibitors of spleen tyrosine kinase (Syk). Bioorg Med Chem Lett13:3111-4 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Low affinity immunoglobulin epsilon Fc receptor |
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| Name: | Low affinity immunoglobulin epsilon Fc receptor |
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| Synonyms: | BLAST-2 | CD23A | CD_antigen=CD23 | CLEC4J | FCE2 | FCER2 | FCER2_HUMAN | Fc-epsilon-RII | IGEBF | Immunoglobulin E-binding factor | Immunoglobulin epsilon Fc receptor | Low affinity immunoglobulin epsilon Fc receptor | Low affinity immunoglobulin epsilon Fc receptor membrane-bound form | Low affinity immunoglobulin epsilon Fc receptor soluble form | Lymphocyte IgE receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36461.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_88888 |
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| Residue: | 321 |
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| Sequence: | MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA
ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL
SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG
TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHV
DYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESM
GPDSRPDPDGRLPTPSAPLHS
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| BDBM50132444 |
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| n/a |
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| Name | BDBM50132444 |
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| Synonyms: | 5-{5-Methoxy-3-[2-oxo-5-sulfamoyl-1,2-dihydro-indol-(3Z)-ylidenemethyl]-indol-1-yl}-pentanoic acid ethyl ester | CHEMBL104651 | ethyl 5-(5-methoxy-3-((2-oxo-5-sulfamoylindolin-3-ylidene)methyl)-1H-indol-1-yl)pentanoate |
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| Type | Small organic molecule |
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| Emp. Form. | C25H27N3O6S |
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| Mol. Mass. | 497.563 |
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| SMILES | CCOC(=O)CCCCn1cc(\C=C2/C(=O)Nc3ccc(cc23)S(N)(=O)=O)c2cc(OC)ccc12 |
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| Structure | 
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