| Reaction Details |
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 | Report a problem with these data |
| Target | Low affinity immunoglobulin epsilon Fc receptor |
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| Ligand | BDBM50132455 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_163803 |
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| EC50 | >10000±n/a nM |
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| Citation |  Lai, JY; Cox, PJ; Patel, R; Sadiq, S; Aldous, DJ; Thurairatnam, S; Smith, K; Wheeler, D; Jagpal, S; Parveen, S; Fenton, G; Harrison, TK; McCarthy, C; Bamborough, P Potent small molecule inhibitors of spleen tyrosine kinase (Syk). Bioorg Med Chem Lett13:3111-4 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Low affinity immunoglobulin epsilon Fc receptor |
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| Name: | Low affinity immunoglobulin epsilon Fc receptor |
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| Synonyms: | BLAST-2 | CD23A | CD_antigen=CD23 | CLEC4J | FCE2 | FCER2 | FCER2_HUMAN | Fc-epsilon-RII | IGEBF | Immunoglobulin E-binding factor | Immunoglobulin epsilon Fc receptor | Low affinity immunoglobulin epsilon Fc receptor | Low affinity immunoglobulin epsilon Fc receptor membrane-bound form | Low affinity immunoglobulin epsilon Fc receptor soluble form | Lymphocyte IgE receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36461.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_88888 |
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| Residue: | 321 |
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| Sequence: | MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA
ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL
SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG
TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHV
DYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESM
GPDSRPDPDGRLPTPSAPLHS
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| BDBM50132455 |
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| n/a |
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| Name | BDBM50132455 |
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| Synonyms: | 3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid dimethylamide | CHEMBL322153 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21N3O4S |
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| Mol. Mass. | 411.474 |
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| SMILES | COc1ccc2n(C)cc(\C=C3/C(=O)Nc4ccc(cc34)S(=O)(=O)N(C)C)c2c1 |
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| Structure | 
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