| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor alpha |
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| Ligand | BDBM24566 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_153484 |
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| Ki | 100±n/a nM |
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| Citation |  Adams, AD; Hu, Z; von Langen, D; Dadiz, A; Elbrecht, A; MacNaul, KL; Berger, JP; Zhou, G; Doebber, TW; Meurer, R; Forrest, MJ; Moller, DE; Jones, AB O-arylmandelic acids as highly selective human PPAR alpha/gamma agonists. Bioorg Med Chem Lett13:3185-90 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor alpha |
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| Name: | Peroxisome proliferator-activated receptor alpha |
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| Synonyms: | Nr1c1 | Nuclear receptor subfamily 1 group C member 1 | PPAR-alpha | PPARA_MOUSE | Peroxisome Proliferator-Activated Receptor alpha | Ppar | Ppara |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52343.28 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_572395 |
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| Residue: | 468 |
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| Sequence: | MVDTESPICPLSPLEADDLESPLSEEFLQEMGNIQEISQSIGEESSGSFGFADYQYLGSC
PGSEGSVITDTLSPASSPSSVSCPVIPASTDESPGSALNIECRICGDKASGYHYGVHACE
GCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSE
KAKLKAEILTCEHDLKDSETADLKSLGKRIHEAYLKNFNMNKVKARVILAGKTSNNPPFV
IHDMETLCMAEKTLVAKMVANGVEDKEAEVRFFHCCQCMSVETVTELTEFAKAIPGFANL
DLNDQVTLLKYGVYEAIFTMLSSLMNKDGMLIAYGNGFITREFLKNLRKPFCDIMEPKFD
FAMKFNALELDDSDISLFVAAIICCGDRPGLLNIGYIEKLQEGIVHVLKLHLQSNHPDDT
FLFPKLLQKMVDLRQLVTEHAQLVQVIKKTESDAALHPLLQEIYRDMY
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| BDBM24566 |
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| n/a |
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| Name | BDBM24566 |
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| Synonyms: | 2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidin-2-yl}sulfanyl)acetic acid | CHEMBL295416 | JMC515449 Compound 1 | Pirinixic acid | Wyeth 14,643 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14ClN3O2S |
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| Mol. Mass. | 323.798 |
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| SMILES | Cc1cccc(Nc2cc(Cl)nc(SCC(O)=O)n2)c1C |
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| Structure | 
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