| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C-C chemokine receptor type 3 |
|---|
| Ligand | BDBM50133796 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_41922 |
|---|
| IC50 | 11±n/a nM |
|---|
| Citation |  Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Design and synthesis of novel CCR3 antagonists. Bioorg Med Chem Lett13:3597-600 (2003) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C-C chemokine receptor type 3 |
|---|
| Name: | C-C chemokine receptor type 3 |
|---|
| Synonyms: | C-C CKR-3 | C-C chemokine receptor type 3 (CCR3) | CC-CKR-3 | CCR-3 | CCR3 | CCR3_HUMAN | CD_antigen=CD193 | CKR3 | CMKBR3 | Eosinophil eotaxin receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 41053.88 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P51677 |
|---|
| Residue: | 355 |
|---|
| Sequence: | MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILI
KYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSE
IFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEE
TLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRL
IFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVI
YAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF
|
|
|
|---|
| BDBM50133796 |
|---|
| n/a |
|---|
| Name | BDBM50133796 |
|---|
| Synonyms: | 1-{(R)-2-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-methyl-ethyl}-3-(3,4,5-trimethoxy-phenyl)-urea | CHEMBL121905 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H36ClN3O4 |
|---|
| Mol. Mass. | 502.045 |
|---|
| SMILES | COc1cc(NC(=O)N[C@H](C)CN2C3CCC2CC(Cc2ccc(Cl)cc2)C3)cc(OC)c1OC |THB:19:18:12:14.15| |
|---|
| Structure | 
|
|---|
Search and Browse
