Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Estrogen receptor beta | ||
| Ligand | BDBM50134329 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_67184 | ||
| EC50 | 3700±n/a nM | ||
| Citation |  Schreiner, EP; Wolff, B; Winiski, AP; Billich, A 6-(2-adamantan-2-ylidene-hydroxybenzoxazole)-O-sulfamate: a potent non-steroidal irreversible inhibitor of human steroid sulfatase. Bioorg Med Chem Lett13:4313-6 (2003) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Estrogen receptor beta | |||
| Name: | Estrogen receptor beta | ||
| Synonyms: | ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta | ||
| Type: | Protein | ||
| Mol. Mass.: | 59238.43 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q92731 | ||
| Residue: | 530 | ||
| Sequence: |
| ||
| BDBM50134329 | |||
| n/a | |||
| Name | BDBM50134329 | ||
| Synonyms: | CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl ester | Sulfamic acid (8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl ester | estra-1,3,5(10)-trien-17-one-3-sulphamate | estrone3-O-sulfamate | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H23NO4S | ||
| Mol. Mass. | 349.445 | ||
| SMILES | C[C@]12CC[C@H]3[C@@H](CCc4cc(OS(N)(=O)=O)ccc34)[C@@H]1CCC2=O | ||
| Structure | 
| ||