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TargetPeptidyl-prolyl cis-trans isomerase A
LigandBDBM50136474
Substrate/Competitorn/a
Meas. Tech.ChEBML_92658
IC50 80.5±n/a nM
Citation Evers, MBarrière, JCBashiardes, GBousseau, ACarry, JCDereu, NFiloche, BHenin, YSablé, SVuilhorgne, MMignani, S Synthesis of non-immunosuppressive cyclophilin-Binding cyclosporin A derivatives as potential anti-HIV-1 drugs. Bioorg Med Chem Lett13:4415-9 (2003) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Peptidyl-prolyl cis-trans isomerase A
Name:Peptidyl-prolyl cis-trans isomerase A
Synonyms:CYPA | CYPA PPIase | Cyclophilin A | Cyclosporin A-binding protein | PPIA | PPIA_HUMAN | PPIase A | Peptidyl-prolyl cis-trans isomerase A | Rotamase A
Type:Protein
Mol. Mass.:18015.32
Organism:Homo sapiens (Human)
Description:P62937
Residue:165
Sequence:
MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGF
MCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTE
WLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
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  Blast E-value cutoff:
BDBM50136474
n/a
NameBDBM50136474
Synonyms:CHEMBL3038092 | Cyclosporin A analogue
TypeSmall organic molecule
Emp. Form.C67H117N13O12S
Mol. Mass.1328.791
SMILESCC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](SCCn2ccnc2)N(C)C1=O)C(C)C
Structure
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