| Reaction Details |
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 | Report a problem with these data |
| Target | T-cell surface glycoprotein CD4 |
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| Ligand | BDBM50123449 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_39920 |
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| IC50 | 130±n/a nM |
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| Citation |  Hegde, VR; Puar, MS; Dai, P; Patel, M; Gullo, VP; Chan, TM; Silver, J; Pramanik, BN; Jenh, CH Condensed aromatic peptide family of microbial metabolites, inhibitors of CD28-CD80 interactions. Bioorg Med Chem Lett13:573-5 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| T-cell surface glycoprotein CD4 |
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| Name: | T-cell surface glycoprotein CD4 |
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| Synonyms: | CD4 | CD4_HUMAN | CD_antigen=CD4 | T-cell surface antigen CD4 | T-cell surface antigen T4/Leu-3 | T-cell surface glycoprotein CD4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51136.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_440402 |
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| Residue: | 458 |
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| Sequence: | MNRGVPFRHLLLVLQLALLPAATQGKKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIK
ILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFPLIIKNLKIEDSDTYICEVEDQKEEVQL
LVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSG
TWTCTVLQNQKKVEFKIDIVVLAFQKASSIVYKKEGEQVEFSFPLAFTVEKLTGSGELWW
QAERASSSKSWITFDLKNKEVSVKRVTQDPKLQMGKKLPLHLTLPQALPQYAGSGNLTLA
LEAKTGKLHQEVNLVVMRATQLQKNLTCEVWGPTSPKLMLSLKLENKEAKVSKREKAVWV
LNPEAGMWQCLLSDSGQVLLESNIKVLPTWSTPVQPMALIVLGGVAGLLLFIGLGIFFCV
RCRHRRRQAERMSQIKRLLSEKKTCQCPHRFQKTCSPI
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| BDBM50123449 |
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| n/a |
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| Name | BDBM50123449 |
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| Synonyms: | CHEMBL437996 | Chloropeptin II | ISOCOMPLESTATIN |
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| Type | Small organic molecule |
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| Emp. Form. | C61H45Cl6N7O15 |
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| Mol. Mass. | 1328.766 |
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| SMILES | [H][C@@]12NC(=O)[C@H](NC(=O)[C@@H](Cc3c[nH]c4cc(ccc34)-c3cc1cc(Oc1ccc(C[C@H](N(C)C(=O)[C@H](NC2=O)c2cc(Cl)c(O)c(Cl)c2)C(=O)N[C@@H](C(O)=O)c2ccc(O)cc2)cc1)c3O)NC(=O)C(=O)c1cc(Cl)c(O)c(Cl)c1)c1cc(Cl)c(O)c(Cl)c1 |r| |
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| Structure | 
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