| Reaction Details |
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 | Report a problem with these data |
| Target | T-cell surface glycoprotein CD4 |
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| Ligand | BDBM50366855 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_39920 |
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| IC50 | 130±n/a nM |
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| Citation |  Hegde, VR; Puar, MS; Dai, P; Patel, M; Gullo, VP; Chan, TM; Silver, J; Pramanik, BN; Jenh, CH Condensed aromatic peptide family of microbial metabolites, inhibitors of CD28-CD80 interactions. Bioorg Med Chem Lett13:573-5 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| T-cell surface glycoprotein CD4 |
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| Name: | T-cell surface glycoprotein CD4 |
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| Synonyms: | CD4 | CD4_HUMAN | CD_antigen=CD4 | T-cell surface antigen CD4 | T-cell surface antigen T4/Leu-3 | T-cell surface glycoprotein CD4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51136.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_440402 |
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| Residue: | 458 |
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| Sequence: | MNRGVPFRHLLLVLQLALLPAATQGKKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIK
ILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFPLIIKNLKIEDSDTYICEVEDQKEEVQL
LVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSG
TWTCTVLQNQKKVEFKIDIVVLAFQKASSIVYKKEGEQVEFSFPLAFTVEKLTGSGELWW
QAERASSSKSWITFDLKNKEVSVKRVTQDPKLQMGKKLPLHLTLPQALPQYAGSGNLTLA
LEAKTGKLHQEVNLVVMRATQLQKNLTCEVWGPTSPKLMLSLKLENKEAKVSKREKAVWV
LNPEAGMWQCLLSDSGQVLLESNIKVLPTWSTPVQPMALIVLGGVAGLLLFIGLGIFFCV
RCRHRRRQAERMSQIKRLLSEKKTCQCPHRFQKTCSPI
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| BDBM50366855 |
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| n/a |
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| Name | BDBM50366855 |
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| Synonyms: | CHEMBL525803 | Chloropeptin |
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| Type | Small organic molecule |
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| Emp. Form. | C61H45Cl6N7O15 |
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| Mol. Mass. | 1328.766 |
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| SMILES | CN1[C@@H](Cc2ccc(Oc3cc4cc(c3O)-c3cccc5c(C[C@@H](NC(=O)C(=O)c6cc(Cl)c(O)c(Cl)c6)C(=O)N[C@H](c6cc(Cl)c(O)c(Cl)c6)C(=O)N[C@H]4C(=O)N[C@H](c4cc(Cl)c(O)c(Cl)c4)C1=O)c[nH]c35)cc2)C(=O)N[C@@H](C(O)=O)c1ccc(O)cc1 |r| |
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| Structure | 
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