Reaction Details |
| Report a problem with these data |
Target | Thromboxane A2 receptor |
---|
Ligand | BDBM50125411 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEBML_158474 |
---|
Ki | >13000±n/a nM |
---|
Citation | Billot, X; Chateauneuf, A; Chauret, N; Denis, D; Greig, G; Mathieu, MC; Metters, KM; Slipetz, DM; Young, RN Discovery of a potent and selective agonist of the prostaglandin EP4 receptor. Bioorg Med Chem Lett13:1129-32 (2003) [PubMed] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Thromboxane A2 receptor |
---|
Name: | Thromboxane A2 receptor |
Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
Type: | Enyzme |
Mol. Mass.: | 37445.28 |
Organism: | Homo sapiens (Human) |
Description: | P21731 |
Residue: | 343 |
Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
|
|
|
BDBM50125411 |
---|
n/a |
---|
Name | BDBM50125411 |
Synonyms: | (R)-5-((E)-(R)-3-Hydroxy-4-phenyl-but-1-enyl)-1-[6-(1H-tetrazol-5-yl)-hexyl]-pyrrolidin-2-one | CHEMBL1794823 | CHEMBL280247 |
Type | Small organic molecule |
Emp. Form. | C21H29N5O2 |
Mol. Mass. | 383.4873 |
SMILES | O[C@H](Cc1ccccc1)\C=C\[C@H]1CCC(=O)N1CCCCCCc1nnn[nH]1 |
Structure |
|