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TargetProstaglandin E2 receptor EP4 subtype
LigandBDBM50125406
Substrate/Competitorn/a
Meas. Tech.ChEBML_158331
Ki 62±n/a nM
Citation Billot, XChateauneuf, AChauret, NDenis, DGreig, GMathieu, MCMetters, KMSlipetz, DMYoung, RN Discovery of a potent and selective agonist of the prostaglandin EP4 receptor. Bioorg Med Chem Lett13:1129-32 (2003) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Prostaglandin E2 receptor EP4 subtype
Name:Prostaglandin E2 receptor EP4 subtype
Synonyms:PE2R4_HUMAN | PGE receptor EP4 subtype | PGE2 receptor EP4 subtype | PTGER2 | PTGER4 | Prostaglandin E2 receptor | Prostanoid EP4 receptor
Type:Enzyme
Mol. Mass.:53134.53
Organism:Homo sapiens (Human)
Description:P35408
Residue:488
Sequence:
MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP
SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSG
QHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPG
MGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSET
LNLSEKCI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50125406
n/a
NameBDBM50125406
Synonyms:7-[(R)-2-((E)-3-Hydroxy-4-methyl-4-phenyl-pent-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acid | CHEMBL278451
TypeSmall organic molecule
Emp. Form.C23H33NO4
Mol. Mass.387.5124
SMILESCC(C)(C(O)\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O)c1ccccc1
Structure
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