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TargetMu-type opioid receptor
LigandBDBM50125688
Substrate/Competitorn/a
Meas. Tech.ChEMBL_149462 (CHEMBL873928)
Ki 178±n/a nM
Citation Stachulski, AVScheinmann, FFerguson, JRLaw, JLLumbard, KWHopkins, PPatel, NClarke, SGloyne, AJoel, SP Structure-activity relationships of some opiate glycosides. Bioorg Med Chem Lett13:1207-14 (2003) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44503.11
Organism:Rattus norvegicus (rat)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50125688
n/a
NameBDBM50125688
Synonyms:3-hydroxy-6-[10-hydroxy-4-methyl-(5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraen-14-yloxy]-3,6-dihydro-2H-2-pyrancarboxylic acid | CHEMBL280206
TypeSmall organic molecule
Emp. Form.C23H25NO7
Mol. Mass.427.4471
SMILESCN1CCC23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4OC1OC(C(O)C=C1)C(O)=O)ccc5O |c:16,26,THB:0:1:12:8.9.10|
Structure
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