Reaction Details | |||
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Target | Carbonic anhydrase 2 | ||
Ligand | BDBM50134329 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_45073 | ||
Ki | 10±n/a nM | ||
Citation | Abbate, F; Winum, JY; Potter, BV; Casini, A; Montero, JL; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase. Bioorg Med Chem Lett14:231-4 (2003) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
Carbonic anhydrase 2 | |||
Name: | Carbonic anhydrase 2 | ||
Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) | ||
Type: | Enzyme | ||
Mol. Mass.: | 29250.71 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P00918 | ||
Residue: | 260 | ||
Sequence: |
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BDBM50134329 | |||
n/a | |||
Name | BDBM50134329 | ||
Synonyms: | CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl ester | Sulfamic acid (8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl ester | estra-1,3,5(10)-trien-17-one-3-sulphamate | estrone3-O-sulfamate | ||
Type | Small organic molecule | ||
Emp. Form. | C18H23NO4S | ||
Mol. Mass. | 349.445 | ||
SMILES | C[C@]12CC[C@H]3[C@@H](CCc4cc(OS(N)(=O)=O)ccc34)[C@@H]1CCC2=O | ||
Structure |