| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 2 |
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| Ligand | BDBM50148399 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_201451 (CHEMBL807596) |
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| IC50 | 0.800000±n/a nM |
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| Citation |  Hale, JJ; Doherty, G; Toth, L; Li, Z; Mills, SG; Hajdu, R; Ann Keohane, C; Rosenbach, M; Milligan, J; Shei, GJ; Chrebet, G; Bergstrom, J; Card, D; Rosen, H; Mandala, S The discovery of 3-(N-alkyl)aminopropylphosphonic acids as potent S1P receptor agonists. Bioorg Med Chem Lett14:3495-9 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 2 |
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| Name: | Sphingosine 1-phosphate receptor 2 |
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| Synonyms: | EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 38883.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay. |
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| Residue: | 353 |
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| Sequence: | MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
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| BDBM50148399 |
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| n/a |
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| Name | BDBM50148399 |
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| Synonyms: | CHEMBL117130 | Phosphoric acid mono-[1-amino-1-hydroxymethyl-3-(4-octyl-phenyl)-propyl] ester |
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| Type | Small organic molecule |
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| Emp. Form. | C18H32NO5P |
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| Mol. Mass. | 373.4241 |
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| SMILES | CCCCCCCCc1ccc(CCC(N)(CO)OP(O)(O)=O)cc1 |
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| Structure | 
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