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TargetCarbonic Anhydrase XIII
LigandBDBM10872
Substrate/Competitorn/a
Meas. Tech.ChEBML_45453
Ki 1.3±n/a nM
Citation Lehtonen JMParkkila SVullo DCasini AScozzafava ASupuran CT Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design. Bioorg Med Chem Lett 14:3757-62 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic Anhydrase XIII
Name:Carbonic anhydrase XIII
Synonyms:CA-XIII | Carbonate dehydratase XIII | Carbonic anhydrase 13
Type:Enzyme
Mol. Mass.:29522.80
Organism:Mus musculus (mouse)
Description:Murine cloned isozyme
Residue:262
Sequence:
MARLSWGYGEHNGPIHWNELFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPASAKII
SNSGHSFNVDFDDTEDKSVLRGGPLTGNYRLRQFHLHWGSADDHGSEHVVDGVRYAAELH
VVHWNSDKYPSFVEAAHESDGLAVLGVFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNF
DPLCLLPSSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAA
FLLSNHRPPQPLKGRRVRASFY
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BDBM10872
n/a
NameBDBM10872
Synonyms:4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-sulfonamide | CHEMBL7146 | aromatic/heteroaromatic sulfonamide 17
TypeSmall organic molecule
Emp. Form.C14H17N3O4S2
Mol. Mass.355.432
SMILESNc1ccc(cc1)S(=O)(=O)NCCc1ccc(cc1)S(N)(=O)=O
Structure
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