Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM50140741 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_145618 |
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Ki | 6532±n/a nM |
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Citation | Chen, Z; Goehring, RR; Valenzano, KJ; Kyle, DJ Design and synthesis of novel small molecule N/OFQ receptor antagonists. Bioorg Med Chem Lett14:1347-51 (2004) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM50140741 |
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n/a |
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Name | BDBM50140741 |
Synonyms: | (3aR,7aR)-1-(1-Cyclooctylmethyl-piperidin-4-yl)-octahydro-benzoimidazol-2-one | CHEMBL280778 |
Type | Small organic molecule |
Emp. Form. | C21H37N3O |
Mol. Mass. | 347.538 |
SMILES | O=C1N[C@@H]2CCCC[C@H]2N1C1CCN(CC2CCCCCCC2)CC1 |
Structure |
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