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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Kappa-type opioid receptor | ||
| Ligand | BDBM50140735 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_145396 | ||
| Ki | 6212±n/a nM | ||
| Citation |  Chen, Z; Goehring, RR; Valenzano, KJ; Kyle, DJ Design and synthesis of novel small molecule N/OFQ receptor antagonists. Bioorg Med Chem Lett14:1347-51 (2004) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Kappa-type opioid receptor | |||
| Name: | Kappa-type opioid receptor | ||
| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 42648.76 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41145 | ||
| Residue: | 380 | ||
| Sequence: |
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| BDBM50140735 | |||
| n/a | |||
| Name | BDBM50140735 | ||
| Synonyms: | (3aR,7aR)-1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-octahydro-benzoimidazol-2-one | CHEMBL286411 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H37N3O | ||
| Mol. Mass. | 347.538 | ||
| SMILES | CC(C)C1CCC(CC1)N1CCC(CC1)N1[C@@H]2CCCC[C@H]2NC1=O |wU:21.24,wD:16.17,(-2.39,-9.62,;-1.32,-8.52,;.17,-8.9,;-1.72,-7.04,;-.64,-5.94,;-1.06,-4.43,;-2.56,-4.06,;-3.65,-5.17,;-3.23,-6.66,;-2.98,-2.57,;-1.9,-1.49,;-2.32,-.01,;-3.79,.39,;-4.88,-.71,;-4.47,-2.17,;-4.21,1.86,;-5.66,2.34,;-6.98,1.58,;-8.33,2.34,;-8.33,3.88,;-6.98,4.65,;-5.66,3.88,;-4.21,4.35,;-3.3,3.1,;-1.76,3.09,)| | ||
| Structure | 
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