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TargetIntegrase
LigandBDBM50123472
Substrate/Competitorn/a
Meas. Tech.ChEMBL_90870 (CHEMBL699303)
IC50 600±n/a nM
Citation Mustata, GIBrigo, ABriggs, JM HIV-1 integrase pharmacophore model derived from diverse classes of inhibitors. Bioorg Med Chem Lett14:1447-54 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Integrase
Name:Integrase
Synonyms:Human immunodeficiency virus type 1 integrase
Type:PROTEIN
Mol. Mass.:32231.48
Organism:Human immunodeficiency virus 1
Description:ChEMBL_90865
Residue:288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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  Blast E-value cutoff:
BDBM50123472
n/a
NameBDBM50123472
Synonyms:7-Benzyl-1,2-dihydroxy-xanthen-9-one | CHEMBL288097
TypeSmall organic molecule
Emp. Form.C20H14O4
Mol. Mass.318.3228
SMILESOc1ccc2oc3ccc(Cc4ccccc4)cc3c(=O)c2c1O
Structure
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