| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50141232 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_90870 (CHEMBL699303) |
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| IC50 | 370±n/a nM |
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| Citation |  Mustata, GI; Brigo, A; Briggs, JM HIV-1 integrase pharmacophore model derived from diverse classes of inhibitors. Bioorg Med Chem Lett14:1447-54 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50141232 |
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| n/a |
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| Name | BDBM50141232 |
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| Synonyms: | 3-[3-((E)-3,4-Dihydroxy-phenyl)-acryloylamino]-2-[(E)-3-(3,4-dihydroxy-phenyl)-acryloyloxy]-propionic acid anion |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18NO9 |
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| Mol. Mass. | 428.3695 |
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| SMILES | Oc1ccc(\C=C\C(=O)NCC(OC(=O)\C=C\c2ccc(O)c(O)c2)C([O-])=O)cc1O |
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| Structure | 
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