| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM50143487 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_3626 |
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| Ki | 0.300000±n/a nM |
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| Citation |  Chang-Fong, J; Rangisetty, JB; Dukat, M; Setola, V; Raffay, T; Roth, B; Glennon, RA 1,2,3,4-tetrahydrocarbazoles as 5-HT6 serotonin receptor ligands. Bioorg Med Chem Lett14:1961-4 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46968.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50406 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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| BDBM50143487 |
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| n/a |
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| Name | BDBM50143487 |
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| Synonyms: | CHEMBL353552 | [9-(2,5-Dimethoxy-benzenesulfonyl)-6-methoxy-2,3,4,9-tetrahydro-1H-carbazol-4-ylmethyl]-dimethyl-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30N2O5S |
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| Mol. Mass. | 458.57 |
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| SMILES | COc1ccc(OC)c(c1)S(=O)(=O)n1c2CCCC(CN(C)C)c2c2cc(OC)ccc12 |
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| Structure | 
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