| Reaction Details |
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 | Report a problem with these data |
| Target | Catechol O-methyltransferase |
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| Ligand | BDBM50367030 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_47238 |
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| Ki | 800000±n/a nM |
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| Citation |  Anderson, GL; Bussolotti, DL; Coward, JK Synthesis and evaluation of some stable multisubstrate adducts as inhibitors of catechol O-methyltransferase. J Med Chem24:1271-7 (1982) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Catechol O-methyltransferase |
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| Name: | Catechol O-methyltransferase |
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| Synonyms: | COMT | COMT_HUMAN | Catechol O-methyltransferase | Catechol O-methyltransferase (MB-COMT) |
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| Type: | Enzyme |
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| Mol. Mass.: | 30030.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21964 |
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| Residue: | 271 |
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| Sequence: | MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRIL
NHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCG
YSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKY
DVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFE
CTHYQSFLEYREVVDGLEKAIYKGPGSEAGP
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| BDBM50367030 |
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| n/a |
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| Name | BDBM50367030 |
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| Synonyms: | CHEMBL539878 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H24N5O4S |
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| Mol. Mass. | 418.489 |
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| SMILES | C[S+](CCc1ccccc1)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| |
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| Structure | 
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