Ki Summary

Reaction Details

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Target

Angiotensin-converting enzyme 2

Ligand

BDBM50367254

Substrate/Competitor

n/a

Meas. Tech.

ChEBML_35979

0.500000±n/a nM

Citation

Elliott, RL; Marks, N; Berg, MJ; Portoghese, PS Synthesis and biological evaluation of phosphonamidate peptide inhibitors of enkephalinase and angiotensin-converting enzyme. J Med Chem28:1208-16 (1985) [PubMed]

More Info.:

Get all data from this article, Assay Method

Angiotensin-converting enzyme 2

Name:

Angiotensin-converting enzyme 2

Synonyms:

ACE2_RAT | Ace2 | Angiotensin-converting enzyme-related carboxypeptidase

Type:

PROTEIN

Mol. Mass.:

92475.04

Organism:

Rattus norvegicus

Description:

ChEMBL_35979

Residue:

805

Sequence:

MSSSCWLLLSLVAVATAQSLIEEKAESFLNKFNQEAEDLSYQSSLASWNYNTNITEENAQ
KMNEAAAKWSAFYEEQSKIAQNFSLQEIQNATIKRQLKALQQSGSSALSPDKNKQLNTIL
NTMSTIYSTGKVCNSMNPQECFLLEPGLDEIMATSTDYNRRLWAWEGWRAEVGKQLRPLY
EEYVVLKNEMARANNYEDYGDYWRGDYEAEGVEGYNYNRNQLIEDVENTFKEIKPLYEQL
HAYVRTKLMEVYPSYISPTGCLPAHLLGDMWGRFWTNLYPLTTPFLQKPNIDVTDAMVNQ
SWDAERIFKEAEKFFVSVGLPQMTPGFWTNSMLTEPGDDRKVVCHPTAWDLGHGDFRIKM
CTKVTMDNFLTAHHEMGHIQYDMAYAKQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKS
IGLLPSNFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFQDKIPREQWTKKWWEM
KREIVGVVEPLPHDETYCDPASLFHVSNDYSFIRYYTRTIYQFQFQEALCQAAKHDGPLH
KCDISNSTEAGQKLLNMLSLGNSGPWTLALENVVGSRNMDVKPLLNYFQPLFVWLKEQNR
NSTVGWSTDWSPYADQSIKVRISLKSALGKNAYEWTDNEMYLFRSSVAYAMREYFSREKN
QTVPFGEADVWVSDLKPRVSFNFFVTSPKNVSDIIPRSEVEEAIRMSRGRINDIFGLNDN
SLEFLGIYPTLKPPYEPPVTIWLIIFGVVMGTVVVGIVILIVTGIKGRKKKNETKREENP
YDSMDIGKGESNAGFQNSDDAQTSF

BDBM50367254

n/a

Name

BDBM50367254

Synonyms:

ENALAPRILAT

Type

Small organic molecule

Emp. Form.

C18H24N2O5

Mol. Mass.

348.3936

SMILES

C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O |r|

Structure