| Reaction Details |
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 | Report a problem with these data |
| Target | Phenylethanolamine N-methyltransferase |
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| Ligand | BDBM50025229 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_153307 |
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| Ki | 4000000±n/a nM |
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| Citation |  Grunewald, GL; Arrington, HS; Bartlett, WJ; Reitz, TJ; Sall, DJ Binding requirements of phenolic phenylethylamines in the benzonorbornene skeleton at the active site of phenylethanolamine N-methyltransferase. J Med Chem29:1972-82 (1986) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Phenylethanolamine N-methyltransferase |
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| Name: | Phenylethanolamine N-methyltransferase |
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| Synonyms: | Noradrenaline N-methyltransferase | PNMT | PNMT_BOVIN | PNMTase |
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| Type: | Enzyme |
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| Mol. Mass.: | 30916.97 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 283 |
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| Sequence: | MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGA
FDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVR
EALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
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| BDBM50025229 |
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| n/a |
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| Name | BDBM50025229 |
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| Synonyms: | 9-Amino-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-ol | CHEMBL418506 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H13NO |
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| Mol. Mass. | 175.227 |
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| SMILES | N[C@@H]1C2CCC1c1c2cccc1O |TLB:11:6:1:4.3,0:1:7.6:4.3,8:7:1:4.3| |
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| Structure | 
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