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TargetPhenylethanolamine N-methyltransferase
LigandBDBM50367283
Substrate/Competitorn/a
Meas. Tech.ChEBML_153307
Ki 3000000±n/a nM
Citation Grunewald, GLArrington, HSBartlett, WJReitz, TJSall, DJ Binding requirements of phenolic phenylethylamines in the benzonorbornene skeleton at the active site of phenylethanolamine N-methyltransferase. J Med Chem29:1972-82 (1986) [PubMed]
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Phenylethanolamine N-methyltransferase
Name:Phenylethanolamine N-methyltransferase
Synonyms:Noradrenaline N-methyltransferase | PNMT | PNMT_BOVIN | PNMTase
Type:Enzyme
Mol. Mass.:30916.97
Organism:Bos taurus (bovine)
Description:n/a
Residue:283
Sequence:
MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGA
FDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVR
EALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
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  Blast E-value cutoff:
BDBM50367283
n/a
NameBDBM50367283
Synonyms:CHEMBL292281
TypeSmall organic molecule
Emp. Form.C11H13NO
Mol. Mass.175.227
SMILESN[C@@H]1CC2CC1c1c2cccc1O |TLB:0:1:4:6.7,THB:11:6:4:1.2,8:7:4:1.2|
Structure
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