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TargetPhenylethanolamine N-methyltransferase
LigandBDBM50024814
Substrate/Competitorn/a
Meas. Tech.ChEBML_153307
Ki 258000±n/a nM
Citation Grunewald, GLArrington, HSBartlett, WJReitz, TJSall, DJ Binding requirements of phenolic phenylethylamines in the benzonorbornene skeleton at the active site of phenylethanolamine N-methyltransferase. J Med Chem29:1972-82 (1986) [PubMed]
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Phenylethanolamine N-methyltransferase
Name:Phenylethanolamine N-methyltransferase
Synonyms:Noradrenaline N-methyltransferase | PNMT | PNMT_BOVIN | PNMTase
Type:Enzyme
Mol. Mass.:30916.97
Organism:Bos taurus (bovine)
Description:n/a
Residue:283
Sequence:
MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGA
FDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVR
EALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
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  Blast E-value cutoff:
BDBM50024814
n/a
NameBDBM50024814
Synonyms:CHEMBL60005 | Tricyclo[6.2.2.0*2,7*]dodeca-2(7),3,5-trien-9-ylamine
TypeSmall organic molecule
Emp. Form.C12H15N
Mol. Mass.173.2542
SMILESN[C@@H]1CC2CCC1c1ccccc21 |TLB:0:1:7.12:5.4,THB:8:7:1.2:5.4,11:12:1.2:5.4|
Structure
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