| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50021322 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_145704 (CHEMBL753912) |
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| Kd | 179±n/a nM |
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| Citation |  Cheng, A; Uyeno, E; Polgar, W; Toll, L; Lawson, JA; DeGraw, JI; Loew, G; Camerman, A; Camerman, N N-substituent modulation of opiate agonist/antagonist activity in resolved 3-methyl-3-(m-hydroxyphenyl)piperidines. J Med Chem29:531-7 (1986) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | KOR-1 | Kappa Opioid Receptor | OPIATE Kappa | OPRK_RAT | Opioid receptor | Oprk1 | Ror-d |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42692.90 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P34975 |
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| Residue: | 380 |
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| Sequence: | MESPIQIFRGEPGPTCAPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAVLSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRV
RNTVQDPASMRDVGGMNKPV
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| BDBM50021322 |
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| n/a |
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| Name | BDBM50021322 |
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| Synonyms: | 3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol | 3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol:hydrochloricacid | CHEMBL150967 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H25NO |
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| Mol. Mass. | 295.4186 |
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| SMILES | CC1(CCCN(CCc2ccccc2)C1)c1cccc(O)c1 |
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| Structure | 
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