| Reaction Details |
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 | Report a problem with these data |
| Target | Renin |
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| Ligand | BDBM50421761 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_154904 (CHEMBL878421) |
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| IC50 | 38±n/a nM |
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| Citation |  Guégan, R; Diaz, J; Cazaubon, C; Beaumont, M; Carlet, C; Clément, J; Demarne, H; Mellet, M; Richaud, JP; Segondy, D Pepstatin analogues as novel renin inhibitors. J Med Chem29:1152-9 (1987) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Renin |
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| Name: | Renin |
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| Synonyms: | RENI_RAT | Ren | Ren1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44272.67 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_222765 |
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| Residue: | 402 |
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| Sequence: | MGGRRMPLWALLLLWTSCSFSLPTDTASFGRILLKKMPSVREILEERGVDMTRISAEWGE
FIKKSSFTNVTSPVVLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYT
ACEIHNLYDSSESSSYMENGTEFTIHYGSGKVKGFLSQDVVTVGGIIVTQTFGEVTELPL
IPFMLAKFDGVLGMGFPAQAVDGVIPVFDHILSQRVLKEEVFSVYYSRESHLLGGEVVLG
GSDPQHYQGNFHYVSISKAGSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSL
QLIMQALGVKEKRANNYVVNCSQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCIL
ALQGLDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR
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| BDBM50421761 |
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| n/a |
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| Name | BDBM50421761 |
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| Synonyms: | CHEMBL2311113 |
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| Type | Small organic molecule |
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| Emp. Form. | C42H63N5O10 |
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| Mol. Mass. | 797.9771 |
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| SMILES | COC(=O)CC(O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CC(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(C)C |
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| Structure | 
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