| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50367422 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_62717 (CHEMBL671460) |
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| Ki | 26±n/a nM |
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| Citation |  Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Antipsychotic activity of substituted gamma-carbolines. J Med Chem30:1818-23 (1987) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50367422 |
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| n/a |
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| Name | BDBM50367422 |
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| Synonyms: | CHEMBL1743935 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18FN3 |
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| Mol. Mass. | 295.354 |
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| SMILES | Fc1ccc2[nH]c3CCN(CCc4ccccn4)Cc3c2c1 |
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| Structure | 
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