| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dipeptidase 1 |
|---|
| Ligand | BDBM50024058 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_216035 |
|---|
| Ki | 160±n/a nM |
|---|
| Citation |  Graham, DW; Ashton, WT; Barash, L; Brown, JE; Brown, RD; Canning, LF; Chen, A; Springer, JP; Rogers, EF Inhibition of the mammalian beta-lactamase renal dipeptidase (dehydropeptidase-I) by (Z)-2-(acylamino)-3-substituted-propenoic acids. J Med Chem30:1074-90 (1987) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Dipeptidase 1 |
|---|
| Name: | Dipeptidase 1 |
|---|
| Synonyms: | DPEP1 | DPEP1_PIG | Dipeptidase 1 | Leukotriene D4 Alpha | Microsomal dipeptidase | RDP | Renal dipeptidase |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44697.32 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | Leukotriene D4 Alpha 0 GUINEA PIG::P22412 |
|---|
| Residue: | 409 |
|---|
| Sequence: | MWTSWWLWPLVAVCAADQFRDLAVRIMQDTPVIDGHNDLPWQLLNLFNNQLQDPGANLSS
LAHTHTNIPKLKAGFVGGQFWSAYVPCDTQNRDAVKRTLEQIDVIQRMCQAYPETFACVT
SSTGIRQAFREGKVASLVGVEGGHSIDSSLGVLRALYHLGMRYMTLTHSCNTPWADNWLV
DTGDDKAQSQGLSHFGQSVVKEMNRLGVMIDLAHVSVATMRAALKLSQAPVIFSHSSAYS
LCPHRRNVPDDVLQLVKETGSLVMVNFYNDYVSCSAKANLSQVADHLDHIKKVAGAAAVG
FGGDYDGVSRVPSGLEDVSKYPDLVAELLRRQWTEAEVRGALADNLLRVFEAVEQASNHA
QVPGEEPIPLGQLEASCRTNYGYSAAPSLHLPPGSLLASLVPLLLLSLP
|
|
|
|---|
| BDBM50024058 |
|---|
| n/a |
|---|
| Name | BDBM50024058 |
|---|
| Synonyms: | 7-(2-Carboxy-2-oxo-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid | CHEMBL417431 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H23NO6S |
|---|
| Mol. Mass. | 357.422 |
|---|
| SMILES | CC1(C)CC1C(=O)NC(=CCCCCSCC(=O)C(O)=O)C(O)=O |w:9.10| |
|---|
| Structure | 
|
|---|
Search and Browse
