| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
|---|
| Ligand | BDBM50019057 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_39181 (CHEMBL654478) |
|---|
| EC50 | >1500±n/a nM |
|---|
| Citation |  Adejare, A; Gusovsky, F; Padgett, W; Creveling, CR; Daly, JW; Kirk, KL Syntheses and adrenergic activities of ring-fluorinated epinephrines. J Med Chem31:1972-7 (1988) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-1 adrenergic receptor |
|---|
| Name: | Beta-1 adrenergic receptor |
|---|
| Synonyms: | ADRB1 | Adrenergic receptor | adrenergic Beta1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 50540.48 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73 |
|---|
| Residue: | 467 |
|---|
| Sequence: | MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAG
MGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVC
TVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRR
PSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANS
AFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDE
DEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
|
|
|
|---|
| BDBM50019057 |
|---|
| n/a |
|---|
| Name | BDBM50019057 |
|---|
| Synonyms: | (+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol | 4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol | 4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol(6-FEPI) | CHEMBL42359 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H12FNO3 |
|---|
| Mol. Mass. | 201.1949 |
|---|
| SMILES | CNCC(O)c1cc(O)c(O)cc1F |
|---|
| Structure | 
|
|---|
Search and Browse
