| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
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| Ligand | BDBM50019060 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_33232 (CHEMBL873047) |
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| Ki | >50000±n/a nM |
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| Citation |  Adejare, A; Gusovsky, F; Padgett, W; Creveling, CR; Daly, JW; Kirk, KL Syntheses and adrenergic activities of ring-fluorinated epinephrines. J Med Chem31:1972-7 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1A adrenergic receptor |
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| Name: | Alpha-1A adrenergic receptor |
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| Synonyms: | ADA1A_HUMAN | ADRA1A | ADRA1C | Adrenergic alpha1A | Alpha 1A-adrenoceptor | Alpha 1A-adrenoreceptor | Alpha adrenergic receptor 1a | Alpha-1C adrenergic receptor | Alpha-adrenergic receptor 1c | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha1 | adrenergic Alpha1C |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 51511.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35348 |
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| Residue: | 466 |
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| Sequence: | MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
APAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTL
HPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSARITVSKDQSSCT
TARVRSKSFLQVCCCVGPSTPSLDKNHQVPTIKVHTISLSENGEEV
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| BDBM50019060 |
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| n/a |
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| Name | BDBM50019060 |
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| Synonyms: | (+/-)4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-diol | 4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-diol | 4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-diol(2-FNE) | CHEMBL287587 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H10FNO3 |
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| Mol. Mass. | 187.1683 |
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| SMILES | NCC(O)c1ccc(O)c(O)c1F |
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| Structure | 
|
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